Utilizing Huangtu Decoction in the clinic, practitioners address acute upper gastrointestinal bleeding, acute coronary syndrome concomitant with acute upper gastrointestinal bleeding, bleeding events related to excessive antiplatelet and anticoagulant medication, unexplained positive fecal occult blood test results, gastrointestinal tumors exhibiting bleeding, thrombocytopenia, and other critical, acute conditions. check details The interplay of Cooking Stove Earthkey, Rehmanniae Radix, and Asini Corii Colla's dosage within the Huangtu Decoction is critical for successful hemostasis.
From the Han dynasty, ZHANG Zhong-jing's “Essentials from the Golden Cabinet” (Jin Kui Yao Lue) first introduced Shenqi Pills. Their effect is to invigorate and nourish the kidney's Qi, primarily targeting kidney Qi and Yang insufficiency. Modern medicine considers kidney Qi to be connected to a range of bodily functions, including heart function, kidney function, immune function, and similar processes. Among the clinical indications of Shenqi Pills are kidney deficiency, abnormal fluid retention, and abnormal urination, specifically characterized as decreased urine output, increased urine output, and difficulty urinating. biomimetic channel For the treatment of heart failure, renal failure, cardiorenal syndrome, and diuretic resistance, as well as chronic degenerative diseases of the endocrine, urological, orthopedic, and other systems, Shenqi Pills have clinical relevance. The use of Shenqi Pills is considered ideal for treating individuals with a delicate constitution and managing critical health issues. Integrating Traditional Chinese Medicine and Western medicine within the framework of 'pathogenesis combined with pathology, and drug properties combined with pharmacology,' yields valuable insights into the significance of classical texts' connotations.
A substantial alteration in human disease types, body composition, and patterns of drug use is evident, necessitating a fresh look at the safety of traditional Chinese medicine (TCM). Non-toxic Traditional Chinese Medicine (TCM) has, unfortunately, frequently been implicated in serious adverse reactions, including liver and kidney damage, significantly altering perceptions of TCM safety and potentially undermining public confidence in TCM's future. The burgeoning era of globalization demands that TCM practitioners prioritize a precise understanding of the challenges associated with TCM safety and proactively address issues in risk assessment and mitigation. Regarding TCM safety, this paper advocates for an objective and nuanced analysis of the existing conditions and problems, alongside a consistent elevation of TCM usage standards. This paper, furthermore, introduces a new conception and methodology in the field of TCM safety. It includes an innovative understanding, two types of evaluation methods, a tri-element injury hypothesis, four-quadrant risk decision-making processes, and a five-grade safety evidence system. The aim is to provide new theories, strategies, methods, and successful case studies for addressing safety issues in TCM.
For generations in West tropical Africa, the leaves of Vernonia amygdalina Delile, belonging to the Asteraceae family and known as 'bitter leaf,' have been utilized as both a food source and a medicine, thanks to their rich biological activity. Southeast Asia and the Fujian and Guangdong provinces of China have recently seen their introduction. While knowledge of the plant's properties in traditional Chinese medicine (TCM) is limited, this scarcity prevents its effective integration with other Chinese medicinal herbs. PubMed, Web of Science, CNKI, Wanfang Data, and VIP databases provided 473 articles on V. amygdalina leaves, which were examined to ascertain their constituent compounds, pharmacological effects, and clinical implications. genetic evolution V. amygdalina leaves display a variety of pharmacological effects, encompassing antimicrobial, hypoglycemic, antihypertensive, lipid-lowering, anti-tumor, anti-inflammatory, antioxidant, and further medicinal properties. The TCM theory identifies the leaves as having a cold property and a bitter-sweet taste, affecting the spleen, liver, stomach, and large intestine. The leaves demonstrate functions such as clearing heat, drying dampness, expelling fire, eliminating toxins, killing insects, and preventing the onset of malaria. These remedies target dampness-heat diarrhea, interior heat, diabetes, malaria, insect accumulation, and eczema. A daily decoction of 5-10 grams of dried leaves, and external application of the right amount of crushed fresh leaves are the ways to utilize them. The medicinal application of V. amygdalina leaves in China is uncommon, owing to their inherent lack of Traditional Chinese Medicine characteristics. Exploring the medicinal attributes of the foliage fosters the introduction of uncommon medicinal plants and the advancement of Traditional Chinese Medicine resources, leading to expanded clinical utilization and research and development of Chinese herbal remedies.
Jingtong Granules' capacity to activate blood, dispel stasis, and move Qi effectively alleviates pain and is a common treatment for cervical radiculopathy in China. Sustained clinical use and supporting data demonstrate the prescription's exceptional effectiveness in mitigating neck, shoulder, and upper limb pain, as well as stiffness, tingling numbness, and the associated pain stemming from this condition. While promising, the application of Jingtong Granules in the clinic has yet to achieve a consistent understanding. Hence, a nationwide gathering of first-line clinical experts and methodological specialists was assembled to develop this expert consensus. By fostering a standardized and rational approach to the use of Jingtong Granules, this expert consensus is anticipated to improve clinical outcomes, decrease medication risks, and ultimately provide significant benefits to patients. From the clinical perspective of experts and the established development standards, the indications, symptoms, advantages in the clinic, and potential negative effects of Jingtong Granules were documented. Clinical problems were formulated based on face-to-to-face interviews with medical practitioners in traditional Chinese and Western medicine and surveys focused on clinical implementations. A consensus on these problems was achieved using the nominal group approach, thereby defining the definitive list. Thirdly, evidence relating to the clinical problems was extracted, followed by a detailed evaluation of the collected evidence. The GRADE system's criteria were used to rate the quality of the evidence. The nominal group technique served to summarize 5 recommendation items and 3 consensus items in the fourth phase of the process. Through expert meetings and letter reviews, opinions and peer reviews on the consensus content were sought. Clinicians in hospitals and primary healthcare facilities can find a valuable resource in the final consensus; it summarizes the evidence on the clinical indications, effectiveness, and safety of Jingtong Granules.
This research sought to determine the effectiveness and safety profile of Biling Weitong Granules in addressing stomach ache disorder. A comprehensive search of Chinese and English electronic databases and trial registration platforms, from their inception to June 10, 2022, unearthed randomized controlled trials (RCTs) exploring the efficacy of Biling Weitong Granules in managing digestive diseases, notably those presenting with stomach ache symptoms. According to the screening criteria, two investigators conducted a comprehensive literature review and extracted the required data. The Cochrane risk-of-bias tool (version 20) facilitated an assessment of the risk of bias in the studies that were included. With RevMan 54 and R 42.2, analyses were performed and summary estimates were produced using fixed or random effects models. Visual analogue scale (VAS) scores and stomach ache disorder symptom scores constituted the principal measures of outcome. The secondary outcomes were measured by the clinical recovery rate, Helicobacter pylori (Hp) eradication rate, and adverse reactions and events. A sample of 2,902 cases were evaluated across 27 independent randomized controlled trials. Biling Weitong Granules, when compared to conventional Western medicine or placebo treatments, demonstrated improvements in VAS scores (SMD = -190, 95% CI [-218, -161], P < 0.00001), stomach ache symptom scores (SMD = -126, 95% CI [-171, -82], P < 0.00001), clinical recovery rates (RR = 185, 95% CI [166, 208], P < 0.00001), and the rate of Hp eradication (RR = 128, 95% CI [120, 137], P < 0.00001), according to the meta-analysis. Biling Weitong Granules' safety analysis exhibited nausea, vomiting, skin rash, diarrhea, a loss of appetite, and a bitter oral sensation, without any serious adverse events being reported. Egger's test, upon analysis, showed no statistically significant results, indicating the absence of publication bias. Biling Weitong Granules for digestive diseases, specifically stomach ache, demonstrated effectiveness in improving VAS and stomach ache symptom scores, contributing to enhanced clinical recovery and Hp eradication rates. These improvements occurred with good safety and without any serious adverse reactions. Nevertheless, the caliber of the initial investigations presented shortcomings and constraints. Future research should adopt unified and standardized outcome detection and evaluation methods, prioritize rigorous study design and execution, and highlight the clinical safety of the medicine to ultimately improve the supporting clinical evidence for clinical application.
Through this study, the correlation between traditional Chinese medicine (TCM) and a decrease in the risk of readmission was explored in patients with rheumatoid arthritis and hypoproteinemia (RA-H). A retrospective cohort study, encompassing 2,437 rheumatoid arthritis patients, was performed using the First Affiliated Hospital of Anhui University of Chinese Medicine's information system database between 2014 and 2021. Remarkably, hypoproteinemia was identified in 476 of these patients.